The primary one is competition from other GLP-1 drugs, especially from Eli Lillys Mounjaro (tirzepatide), which has shown greater efficacy in weight loss and diabetes control
Research, which is still mostly in mice and cells with limited human data as of mid-2026, looks at it for metabolism, insulin sensitivity, and the AMPK energy pathway
Experience diastasis recti causing a protruding pouch even at a healthy weight
However, its anorectic effects and impact on weight loss are comparatively modest relative to those observed with GLP-1R agonism
Clinical trials have shown significant reductions in baseline body weight over extended treatment durations, particularly when dosing is escalated gradually under medical supervision
Pero esta demanda inicial del nuevo medicamento para bajar de peso incluso pareca haber excedido la oferta, segn los analistas de Jefferies , lo que podra haber provocado algunos retrasos en el surtido de recetas